o Development of Elysium "Nose-Throat" Nano-spray
ELYSIUM
Cell Bio ITA has developed a novel "DIETARY SUPPLEMENT" Elysium Nose-Throat is a dietary supplement based on Mullein,
Thyme, Propolis and Polyphosphates. The product is registered "AS FOOD SUPPLEMENTS" at the MINISTRY OF HEALTH code NO. 163054. The product is Patented by Elysium Cell bio ITA srl 80145 – Naples (n. 102023000016338,
August 2023; n. 102024000005170, March 2024)
ELYSIUM Cell Bio ITA is focused on translational studies (in vitro and in vivo) on metastatic brain tumors and breast cancers (e.g., Medulloblastoma and Triple Negative Breast Cancer, respectively) by studying those changes occurring within the tumor microenvironment affecting the cellular metabolism due to the application of new small molecules able to inhibit the Warburg effect and enhance the immunotherapeutic benefits.
Therapeutics
ELYSIUM Cell Bio ITA has developed non toxic molecules capable to target Prune1 in tumorigenic cells by enhancing its intracellular degradation, thus inhibiting its related metastatic axis, by reducing TGF-beta signalling in the tumor microenvironment and affecting the epithelial to mesenchymal transition.
Patent related to this project: European IP 28/10/2022 n. EP22204452, “PRUNE1 INHIBITORS AND THERAPEUTIC USE THEREOF”.
References related to this issue:
https://pubmed.ncbi.nlm.nih.gov/29490009/; https://www.sciencedirect.com/science/article/pii/S2589004220311354